Browsing by Author "Kagira, John Maina"
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Comparative Pathogenicity of Trypanosoma brucei rhodesiense Strains in Swiss white Mice and mastomys natalensis Rats
Muchiri, Margaret Wanjiku; Ndung'u, Kariuki; Kibugu, James Karuku; Thuita, John Kibuthu; Gitonga, Purity Kaari; Ngae, Geoffrey Njuguna; Mdachi, Raymond Ellie; Kagira, John Maina (2015)Abstract We evaluated Mastomys natelensis rat as an animal model for Rhodesian sleeping sickness. Parasitaemia, clinical and pathological characteristics induced by T. b. rhodesiense isolates, KETRI 3439, 3622 and 3637 ... -
Proinflammatory cytokine expression in the early phase of Trypanosoma brucei rhodesiense infection in vervet monkeys (Cercopithecus aethiops)
Maina, Naomi; Ngotho, Joseph Maina; Were, Tom; Thuita, John Kibuthu; Mwangangi, David Mumo; Kagira, John Maina; Ndung'u, Joseph Mathu; Sternberg, Jeremy (2004)A vervet monkey model of trypanosomiasis was used to study inflammatory cytokine responses in serum and cerebrospinal fuid (CSF). Gamma interferon levels were transiently up-regulated in serum between days 6 and 8 of ...