Browsing School of Health Sciences & School of Nursing by Author "King, Christopher L"
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Birthweight in offspring of mothers with high prevalence of helminth and malaria infection in coastal Kenya
Fairley, Jessica K; Bisanzio, Donal; King, Charles H; Kitron, Uriel; Mungai, Peter; Muchiri, Eric; King, Christopher L; Malhotra, Indu (The American Society of Tropical Medicine and Hygiene, 2013)Results of studies on the associations of maternal helminth infection and malaria-helminth co-infection on birth outcomes have been mixed. A group of 696 pregnant women from the Kwale district in Kenya were recruited and ... -
In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
Steiner, Kevin L; Malhotra, Indu; Mungai, Peter L; Muchiri, Eric M; Dent, Arlene E; King, Christopher L (Academic Press, 2012)In utero priming to malaria antigens renders cord blood mononuclear cells (CBMC) more susceptible to productive HIV infection in vitro in the absence of exogenous stimulation. This provides a unique model to better understand ... -
In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
Steiner, Kevin L; Malhotra, Indu; Mungai, Peter L; Muchiri, Eric M; Dent, Arlene E; King, Christopher L (Academic Press, 2012)The HIV-1 CCR5 co-receptor is a member of the chemokine receptor family of G-protein coupled receptors;for which a number of small molecule antagonists, such as vicriviroc (VCV), have been developed to inhibit HIV-1 R5-tropic ...