Browsing School of Health Sciences & School of Nursing by Author "Steiner, Kevin L"
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In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
Steiner, Kevin L; Malhotra, Indu; Mungai, Peter L; Muchiri, Eric M; Dent, Arlene E; King, Christopher L (Academic Press, 2012)In utero priming to malaria antigens renders cord blood mononuclear cells (CBMC) more susceptible to productive HIV infection in vitro in the absence of exogenous stimulation. This provides a unique model to better understand ... -
In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
Steiner, Kevin L; Malhotra, Indu; Mungai, Peter L; Muchiri, Eric M; Dent, Arlene E; King, Christopher L (Academic Press, 2012)The HIV-1 CCR5 co-receptor is a member of the chemokine receptor family of G-protein coupled receptors;for which a number of small molecule antagonists, such as vicriviroc (VCV), have been developed to inhibit HIV-1 R5-tropic ...