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Dengue and West Nile Virus transmission in children and adults in coastal Kenya
(The American Society of Tropical Medicine and Hygiene, 2016)
Dengue virus (DENV) and West Nile virus (WNV) are important reemerging arboviruses that are under-recognized
in many parts of Africa due to lack of surveillance. As a part of a study on flavivirus, alphavirus, and parasite ...
Development of a specimen-sparing multichannel bead assay to detect antiparasite IgG4 for the diagnosis of Schistosoma and Wuchereria infections on the coast of Kenya
(The American Society of Tropical Medicine and Hygiene, 2014)
To better delineate the impact of parasitic coinfection in coastal Kenya, we developed a novel specimen-sparing bead assay using multiplex flow immunoassay (MFI) technology to simultaneously measure serum or plasma ...
Impact of polyparasitic infections on anemia and undernutrition among Kenyan children living in a Schistosoma haematobium-endemic area
(The American Society of Tropical Medicine and Hygiene, 2013)
We measured prevalence of Schistosoma haematobium, Wuchereria bancrofti,Plasmodium falciparum, hookworm, and other geohelminths among school-aged children in four endemic villages in Kwale County, Kenya and explored the ...
Rift Valley Fever Seroprevalence in Coastal Kenya
(The American Society of Tropical Medicine and Hygiene, 2017)
Rift Valley fever virus (RVFV) causes severe disease in both animals and humans, resulting in significant economic and public health damages. The objective of this study was to measure RVFV seroprevalence in six coastal ...
Anemia among children exposed to polyparasitism in coastal Kenya
(The American Society of Tropical Medicine and Hygiene, 2015)
Anemia represents a substantial problem for children living in areas with limited resources and significant
parasite burden. We performed a cross-sectional study of 254 Kenyan preschool- and early school-age children in ...
In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
(Academic Press, 2012)
In utero priming to malaria antigens renders cord blood mononuclear cells (CBMC) more susceptible to productive HIV infection in vitro in the absence of exogenous stimulation. This provides a unique model to better understand ...
Evaluation of the health-related quality of life of children in Schistosoma haematobium-endemic communities in Kenya: a cross-sectional study
(Public Library of Science, 2013)
Schistosomiasis remains a global public health challenge, with 93% of the, 237 million infections occurring in sub-Saharan Africa. Though rarely fatal, its recurring nature makes it a lifetime disorder with significant ...
Projecting the long-term impact of school-or community-based mass-treatment interventions for control of Schistosoma infection
(Public Library of Science, 2012)
Schistosomiasis remains a significant health burden in many areas of the world. Morbidity control, focused on
limiting infection intensity through periodic delivery of anti-schistosomal medicines, is the thrust of current ...
In utero activation of fetal memory T cells alters host regulatory gene expression and affects HIV susceptibility
(Academic Press, 2012)
The HIV-1 CCR5 co-receptor is a member of the chemokine receptor family of G-protein coupled receptors;for which a number of small molecule antagonists, such as vicriviroc (VCV), have been developed to inhibit HIV-1 R5-tropic ...
Differentiating Schistosoma haematobium from related animal schistosomes by PCR amplifying inter-repeat sequences flanking newly selected repeated sequences
(The American Society of Tropical Medicine and Hygiene, 2012)
In schistosomiasis elimination programs, successful discrimination of Schistosoma haematobium from the related animal
Schistosoma parasites will be essential for accurate detection of human parasite transmission. Polymerase ...