Browsing by Author "Barrett, Michael P"
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Diamidines for human African trypanosomiasis
Paine, Mary F; Wang, Michael Zhuo; Generaux, Claudia N; Boykin, David W; Wilson, W David; Koning, Harry P De; Olson, Carol A; Pohlig, Gabriele; Burri, Christian; Brun, Reto; Murilla, Grace A; Thuita, John K; Barrett, Michael P; Tidwell, Richard R (Thomson Reuters, 2010)Aromatic diamidines are potent trypanocides. Pentamidine, a diamidine, has been used for more than 60 years to treat human African trypanosomiasis (HAT); however, the drug must be administered parenterally and is active ...