Browsing by Author "Hall, James Edwin"

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    • Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypano 

      Thuita, John K; Wolf, Kristina K; Murilla, Grace A; Liu, Qiang; Mutuku, James N; Chen, Yao; Bridges, Arlene S; Mdachi, Raymond E; Ismail, Mohamed A; Ching, Shelley; Boykin, David W; Hall, James Edwin; Tidwell, Richard R; Paine, Mary F; Brun, Reto; Wang, Michael Zhuo (PLOS, 2013)
      There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs ...