Browsing Staff Publications by Subject "DB289"
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Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis
(Elsevier, 2008)The choice of drugs for the treatment of sleeping sickness is extremely limited. To redress this situation, the recently synthesised diamidine, 2,5-bis(4-amidinophenyl)-furan (DB75, furamidine) and its methamidoxime prodrug, ...