Staff Publications: Recent submissions
Now showing items 241-260 of 919
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Resilience of soils and vegetation subjected to different grazing intensities in a semi-arid rangeland of Kenya
(Taylor & Francis, 1997)The resilience of rangeland soils and vegetation to different levels of grazing is still poorly understood. A study was conducted to determine the recovery of a rangeland grazed at different intensities and allowed a ... -
Tree Layer Dynamics under Different Land Uses and Soils in Semi-Arid Areas of Kenya
(2002)A study was conducted to characterize the main factors critical to the distribution of key wood species and quantify the effects of land use on the tree layer in a semi-arid area of Kenya. Units studied were small-scale ... -
Proinflammatory cytokine expression in the early phase of Trypanosoma brucei rhodesiense infection in vervet monkeys (Cercopithecus aethiops)
(2004)A vervet monkey model of trypanosomiasis was used to study inflammatory cytokine responses in serum and cerebrospinal fuid (CSF). Gamma interferon levels were transiently up-regulated in serum between days 6 and 8 of ... -
Influence of cyclophosphamide on the haematological profile of laboratory bred African soft-furred rats (Mastomys natalensis)
(2005)The African soft-furred rat (Mastomys natalensis) has been shown to be a possible model for propagation of Trypanosoma brucei gambiense. This study aimed at determining the baseline biological reference values and reproductive ... -
Lymphosarcoma in Adult African Green Monkeys (Chlorocebus Aethiops)
(Journal of Laboratory Animal Scienc, 2007)The clinical observations and pathological manifestations of lymphosarcoma in two African green monkeys are described. Monkeys had been caught from the wild. Prior to the development of neoplasms one monkey had been ... -
A Local Directional Ternary Pattern Texture Descriptor for Mammographic Breast Cancer Classification
(International Journal of Computer Applications, 2020)Breast cancer is a top killer illness for women globally, but early and effective screening can increase their survival rate. Mammography is the tool used by a radiologist to screen for breast cancer, however, a radiologist ... -
A Review on Feature Selection Methods For Classification Tasks
(International Journal of Computer Applications Technology and Research, 2016)In recent years, application of feature selection methods in medical datasets has greatly increased. The challenging task in feature selection is how to obtain an optimal subset of relevant and non redundant features which ... -
Supplier evaluation and Selection. A review
(Journal of Ultra Computer & Information Technology, 2019) -
Phenomenology Approach Applicability in Information Systems and Technology Field
(Horizon Research Publishing Corporation, 2020)Phenomenology is a research approach that is uniquely positioned to help scholars learn from the experience of others. Even though it is a powerful research approach, the nature of phenomenology is qualitatively requiring ... -
ICT Adoption in the Educational Management of Primary Schools in Kenya
(Universal Journal of Communications and Network, 2020)Information Communication Technology (ICT) plays an important role in enhancing the quality of education. The adoption of ICT for educational management in developed countries has significantly transformed the education ... -
Breast Cancer Classification using Local Directional Ternary Patterns
(International Journal of Computer Applications, 2020)Local texture descriptors have outperformed holistic texture descriptors in various pattern recognition applications. However, the local descriptors have limitations that can compromise ... -
Development of a rodent model for late stage rhodesian sleeping sickness
(National Research Center for Protozoan Diseases, 2007)A mouse model of Trypanosoma brucei rhodesiense that can be used in pathogenesis and drug studies for Human African Trypanosomosis (HAT) has so far not been developed. In an attempt to develop such a model, a study was ... -
Hematological changes in vervet monkeys (Chlorocebus aethiops) during eight months' adaptation to captivity
(American Journal of Primatology, 2007)This study investigated fluctuations in hematological values of 50 wild-caught vervet monkeys (African green monkeys, grivets, Chlorocebus aethiops) during habituation to captivity. The monkeys were categorized into four ... -
Haematology of experimental Trypanosoma brucei rhodesiense infection in vervet monkeys
(African Journal of Health Sciences,, 2006)Haematological aberrations associated with human infective trypanosomes were investigated in the vervet monkey model of the Rhodesian sleeping sickness. Four monkeys were infected intravenously with 104 Trypanosoma brucei ... -
Trypanosoma brucei rhodesiense transmitted by a single tsetse fly bite in vervet monkeys as a model of Human African Trypanosomiasis.
(PLOS, 2008)We have investigated the pathogenicity of tsetse (Glossina pallidipes)-transmitted cloned strains of Trypanosoma brucei rhodesiense in vervet monkeys. Tsetse flies were confirmed to have mature trypanosome infections by ... -
Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in vervet monkeys after oral administration
(American Society for Microbiology, 2009)10 to 30 days to facilitate treatment with parenterally administered medicines. The efficacy of a novel orally administered prodrug, 2,5-bis(4-amidinophenyl)-furan-bis-O-methlylamidoxime (pafuramidine, DB289), was tested ... -
Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis
(Elsevier, 2008)The choice of drugs for the treatment of sleeping sickness is extremely limited. To redress this situation, the recently synthesised diamidine, 2,5-bis(4-amidinophenyl)-furan (DB75, furamidine) and its methamidoxime prodrug, ... -
Diamidines for human African trypanosomiasis
(Thomson Reuters, 2010)Aromatic diamidines are potent trypanocides. Pentamidine, a diamidine, has been used for more than 60 years to treat human African trypanosomiasis (HAT); however, the drug must be administered parenterally and is active ... -
Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis
(PLOS, 2012)Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second ... -
Invasive Plant Species and Biomass Production in Savannas
(InTech: Biomass and Remote Sensing of Biomass, 2011)Savannas are the second largest biome accounting for c. 30% of terrestrial production. Tropical savannas are distributed largely in Africa, Australia and South America occurring between tropical ...