Browsing School of Agriculture & Food Science by Author "Brun, R."
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Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis
Thuita, John K.; Karanja, S.M.; Wenzler, T.; Mdachi, R.E.; Ngotho, J.M.; Tidwell, R.; Brun, R. (Elsevier, 2008)The choice of drugs for the treatment of sleeping sickness is extremely limited. To redress this situation, the recently synthesised diamidine, 2,5-bis(4-amidinophenyl)-furan (DB75, furamidine) and its methamidoxime prodrug, ...