Browsing School of Agriculture & Food Science by Author "Liu, Qiang"
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Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys
Thuita, John K.; Wolf, Kristina K.; Murilla, Grace A.; Bridges, Arlene S.; Boykin, David W.; Mutuku, James N.; Liu, Qiang; Jones, Susan K.; Gem, Charles O.; Tidwell, Richard R.; Wang, Michael Z.; Paine, Mary F.; Brun, Reto (PLOS, 2014)Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the second stage (central ... -
Prediction of moisture content of Agaricus bisporus slices as affected by vacuum freeze drying using hyperspectral imaging
Bai, Shiqi; Xiao, Kunpeng; Liu, Qiang; Mariga, Alfred Mugambi; Yang, Wenjian; Fang, Yong; Hu, Qiuhui; Gao, Haiyan; Chen, Hangjun; Pei, Fei (Elsevier, 2024-01-03)Moisture content (MC) is a crucial indicator used for assessing the degree of freeze-drying (FD) of Agaricus bisporus. This study illustrated a novel approach to quickly and visually detect MC in A. bisporus during FD using ... -
Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypano
Thuita, John K; Wolf, Kristina K; Murilla, Grace A; Liu, Qiang; Mutuku, James N; Chen, Yao; Bridges, Arlene S; Mdachi, Raymond E; Ismail, Mohamed A; Ching, Shelley; Boykin, David W; Hall, James Edwin; Tidwell, Richard R; Paine, Mary F; Brun, Reto; Wang, Michael Zhuo (PLOS, 2013)There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs ...