| dc.contributor.author | Makembo, George |  | 
| dc.contributor.author | Karanja, Stephen |  | 
| dc.contributor.author | Theuri, David Mwangi |  | 
| dc.date.accessioned | 2021-01-29T07:22:54Z |  | 
| dc.date.available | 2021-01-29T07:22:54Z |  | 
| dc.date.issued | 2017 |  | 
| dc.identifier.citation | George, M., Stephen, K., & Theuri, D. (2017). Modelling Miraa Addiction like a Disease Incorporating Voluntary Quitting. Journal of Advances in Mathematics and Computer Science, 24(4), 1-19. https://doi.org/10.9734/JAMCS/2017/35953 | en_US | 
| dc.identifier.uri | https://doi.org/10.9734/JAMCS/2017/35953 |  | 
| dc.identifier.uri | http://repository.must.ac.ke/handle/123456789/274 |  | 
| dc.description.abstract | This  study  presented  a  deterministic  model  of  miraa  addiction  based  on  three  compartmental  classes incorporating miraaspecific attributes as well as the aspect of voluntary quitting. Our model was based on SIS classical infectious model classes with Susceptible(S) and Infected (I) adopted as Light user (L) and Addicted (A) in our model. From the model flow chart, non linear differential equations are deduced. The  basic  reproduction  number(R)was  determined  using  next  generation  method.  Positivity  and boundedness of the solution was investigated and the system of equations was found to lie in the feasible region. Miraa equilibrium points were determined and the condition necessary for the existence of miraa persistent equilibrium point was found to beR>1.  The conditions necessary for both local and global asymptotic  stability  of  equilibrium  points  were  determined.  Sensitivity  analysis  of  the Rwas investigated  using  partial  differentiation  and  then  confirmed  using  normalized  sensitivity  analysis. Simulations were carried out using MATLAB ODE 45 inbuilt solver. Sensitivity analysis results revealed that  the Rwas  directly  proportional  to  the  rate  of  quitting  from  addict  to  light  user  but  inversely proportional to the rate of quitting from light user to susceptible. Therefore the rate of individuals moving from light user class to susceptible classes has higher impact on reducing the burden of miraa addiction than  the  rate  of  individuals  moving  from  addict  to  light  user.  This  study  used  theoretical  data  and parameters,  future  studies  should  consider  fitting  model  to  real  data.  The  findings  of  this  study  will provide the stake holders including the government, NACADA, rehabilitation centres and general public with information of the spread of the addiction so that necessary measures may be taken to address the challenges. The model can  find application  in  predicting future trends  which is necessary  for planning.  Control strategies can be instituted with the help of the model. | en_US | 
| dc.language.iso | en | en_US | 
| dc.publisher | Journal of Advances in Mathematics and Computer Science | en_US | 
| dc.subject | Modelling | en_US | 
| dc.subject | Basic reproduction number | en_US | 
| dc.subject | Stability | en_US | 
| dc.subject | Normalized sensitivity analysis and simulation | en_US | 
| dc.title | Modelling Miraa Addiction like a Disease Incorporating Voluntary Quitting | en_US | 
| dc.type | Book | en_US |