| dc.contributor.author | Mulinge, Erastus | |
| dc.contributor.author | Zeyhle, Eberhard | |
| dc.contributor.author | Mbae, Cecilia | |
| dc.contributor.author | Gitau, Lucy | |
| dc.contributor.author | Kaburu, Timothy | |
| dc.contributor.author | Magambo, Japhet | |
| dc.contributor.author | Mackenstedt, Ute | |
| dc.contributor.author | Romig, Thomas | |
| dc.contributor.author | Kern, Peter | |
| dc.contributor.author | Wassermann, Marion | |
| dc.date.accessioned | 2023-04-24T05:50:10Z | |
| dc.date.available | 2023-04-24T05:50:10Z | |
| dc.date.issued | 2023-02-27 | |
| dc.identifier.citation | Mulinge, E., Zeyhle, E., Mbae, C., Gitau, L., Kaburu, T., Magambo, J., ... & Wassermann, M. (2023). Cystic echinococcosis in donkeys in eastern Africa. Parasitology, 1-8. | en_US |
| dc.identifier.uri | DOI: https://doi.org/10.1017/S0031182023000173 | |
| dc.identifier.uri | http://repository.must.ac.ke/handle/123456789/861 | |
| dc.description.abstract | Cystic Echinococcosis (CE) is endemic in humans and domestic animals in Eastern Africa. All the species of the Echinococcus granulosus sensu lato complex have been reported in this region except for E. equinus, possibly due to the small number of studies involving equids.
This study reports the frequency of different Echinococcus species in donkeys from eastern
Africa. A total of 5961 donkeys were examined during meat inspection in 3 slaughterhouses
in Kenya. Identification of Echinococcus spp. was achieved through polymerase chain reaction-restriction fragment-length polymorphism and sequencing of the mitochondrial nicotinamide adenine dinucleotide (NADH) dehydrogenase subunit 1 gene. The prevalence of
CE was 5.7% (337/5961). The 263 genotyped cysts belonged to E. equinus (n = 163), E. granulosus sensu stricto (n = 70), E. canadensis (G6/7) (n = 26) and E. ortleppi (n = 4). One donkey
harboured a metacestode of Spirometra theileri. All E. equinus cases, except 2, originated from
southern Ethiopia, whereas the other species were more evenly distributed across the study
area. Most of the cysts belonging to E. equinus were fertile (111/163), while those of the
other species were non-fertile. This is the first report of Echinococcus spp. in donkeys from
sub-Saharan Africa and the first confirmation of E. equinus in East Africa. The frequent
fertility of E. equinus cysts in donkeys affirms their suitability as intermediate hosts of this
species, while low frequency and cyst fertility suggest a marginal role of donkeys in the
transmission of E. granulosus s. s., E. canadensis (G6/7) and E. ortleppi. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Cambridge University Press | en_US |
| dc.subject | Cystic echinococcosis | en_US |
| dc.subject | Donkeys | en_US |
| dc.subject | Eastern Africa | en_US |
| dc.subject | Echinococcus equinus | en_US |
| dc.subject | Echinococcus granulosus sensu lato | en_US |
| dc.title | Cystic Echinococcosis in Donkeys in Eastern Africa | en_US |
| dc.type | Article | en_US |
